I've seen up to an 1" difference from side to side on a car with factory quarters and axle. If everything is centered and equal, 295 width will fit as @6PKRTSE has on his Challenger. Quality control wasn't very good on our E-Bodies unfortunately. 275 in the rear should fit in any factory E-Body, but if I remember correctly, someone posted they had more than an inch difference! So there's that possibility too! Sigh!
Up front I run an MT 26x10 tire on a 15x8 wheel with 4.5" backspace. Fits well. BTW, that about a 255/60 in metric terms.
I test fit a 26x12 on a 15x10 rim. Won't work because you can't get enough backspace to get it under the wheel lip and clear the control arm (control arm limits backspace to 4.75" with a 15" rim). You would need to significantly flare the fender to allow this to fit. However, if you go to a 17" rim, that diameter is larger enough to clear the control arm and you can run more backspace (5.5-5.75 inches) and have enough room to potentially fit a 295-315 in the front. However, back space and alignment have to be spot on and you will still need to roll the lip.
I do run the 26x12 on the rear.
Picture on the ground is 26x10. Pic down the side of the car is 26x12 on the front.